Cargando…

Ca(2+) cycling properties are conserved despite bradycardic effects of heart failure in sinoatrial node cells

Background: In animal models of heart failure (HF), heart rate decreases due to an increase in intrinsic cycle length (CL) of the sinoatrial node (SAN). Pacemaker activity of SAN cells is complex and modulated by the membrane clock, i.e., the ensemble of voltage gated ion channels and electrogenic p...

Descripción completa

Detalles Bibliográficos
Autores principales: Verkerk, Arie O., van Borren, Marcel M. G. J., van Ginneken, Antoni C. G., Wilders, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313601/
https://www.ncbi.nlm.nih.gov/pubmed/25698973
http://dx.doi.org/10.3389/fphys.2015.00018