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Ca(2+) cycling properties are conserved despite bradycardic effects of heart failure in sinoatrial node cells
Background: In animal models of heart failure (HF), heart rate decreases due to an increase in intrinsic cycle length (CL) of the sinoatrial node (SAN). Pacemaker activity of SAN cells is complex and modulated by the membrane clock, i.e., the ensemble of voltage gated ion channels and electrogenic p...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313601/ https://www.ncbi.nlm.nih.gov/pubmed/25698973 http://dx.doi.org/10.3389/fphys.2015.00018 |