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Therapeutic Re-Activation of Protein Phosphatase 2A in Acute Myeloid Leukemia
Protein phosphatase 2A (PP2A) is a serine/threonine phosphatase that is required for normal cell growth and development. PP2A is a potent tumor suppressor, which is inactivated in cancer cells as a result of genetic deletions and mutations. In myeloid leukemias, genes encoding PP2A subunits are gene...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313608/ https://www.ncbi.nlm.nih.gov/pubmed/25699237 http://dx.doi.org/10.3389/fonc.2015.00016 |