Therapeutic Re-Activation of Protein Phosphatase 2A in Acute Myeloid Leukemia

Protein phosphatase 2A (PP2A) is a serine/threonine phosphatase that is required for normal cell growth and development. PP2A is a potent tumor suppressor, which is inactivated in cancer cells as a result of genetic deletions and mutations. In myeloid leukemias, genes encoding PP2A subunits are gene...

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Detalles Bibliográficos
Autores principales: Ramaswamy, Kavitha, Spitzer, Barbara, Kentsis, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313608/
https://www.ncbi.nlm.nih.gov/pubmed/25699237
http://dx.doi.org/10.3389/fonc.2015.00016

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