Dietary restriction protects against experimental cerebral malaria via leptin modulation and T cell mTORC1 suppression

Host nutrition can affect the outcome of parasitic diseases through metabolic effects on host immunity and/or the parasite. Here we show that modulation of mouse immunometabolism through brief restriction of food intake (dietary restriction, DR) prevents neuropathology in experimental cerebral malar...

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Detalles Bibliográficos
Autores principales: Mejia, Pedro, Treviño-Villarreal, J. Humberto, Hine, Christopher, Harputlugil, Eylul, Lang, Samantha, Calay, Ediz, Rogers, Rick, Wirth, Dyann, Duraisingh, Manoj T., Mitchell, James R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313624/
https://www.ncbi.nlm.nih.gov/pubmed/25636003
http://dx.doi.org/10.1038/ncomms7050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313624/
https://www.ncbi.nlm.nih.gov/pubmed/25636003
http://dx.doi.org/10.1038/ncomms7050

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