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Mitochondrial function in neuronal cells depends on p97/VCP/Cdc48-mediated quality control
Maintaining mitochondrial function is essential for neuronal survival and offers protection against neurodegeneration. Ubiquitin-mediated, proteasome-dependent protein degradation in the form of outer mitochondrial membrane associated degradation (OMMAD) was shown to play roles in maintenance of mit...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313695/ https://www.ncbi.nlm.nih.gov/pubmed/25698929 http://dx.doi.org/10.3389/fncel.2015.00016 |