Cargando…

Mitochondrial function in neuronal cells depends on p97/VCP/Cdc48-mediated quality control

Maintaining mitochondrial function is essential for neuronal survival and offers protection against neurodegeneration. Ubiquitin-mediated, proteasome-dependent protein degradation in the form of outer mitochondrial membrane associated degradation (OMMAD) was shown to play roles in maintenance of mit...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, Lei, Hemion, Charles, Pinho Ferreira Bento, Ana C., Bippes, Claudia C., Flammer, Josef, Neutzner, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313695/
https://www.ncbi.nlm.nih.gov/pubmed/25698929
http://dx.doi.org/10.3389/fncel.2015.00016