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Pannexin2 oligomers localize in the membranes of endosomal vesicles in mammalian cells while Pannexin1 channels traffic to the plasma membrane

Pannexin2 (Panx2) is the largest of three members of the pannexin proteins. Pannexins are topologically related to connexins and innexins, but serve different functional roles than forming gap junctions. We previously showed that pannexins form oligomeric channels but unlike connexins and innexins,...

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Detalles Bibliográficos
Autores principales: Boassa, Daniela, Nguyen, Phuong, Hu, Junru, Ellisman, Mark H., Sosinsky, Gina E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313697/
https://www.ncbi.nlm.nih.gov/pubmed/25698922
http://dx.doi.org/10.3389/fncel.2014.00468