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Pannexin2 oligomers localize in the membranes of endosomal vesicles in mammalian cells while Pannexin1 channels traffic to the plasma membrane
Pannexin2 (Panx2) is the largest of three members of the pannexin proteins. Pannexins are topologically related to connexins and innexins, but serve different functional roles than forming gap junctions. We previously showed that pannexins form oligomeric channels but unlike connexins and innexins,...
Autores principales: | Boassa, Daniela, Nguyen, Phuong, Hu, Junru, Ellisman, Mark H., Sosinsky, Gina E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313697/ https://www.ncbi.nlm.nih.gov/pubmed/25698922 http://dx.doi.org/10.3389/fncel.2014.00468 |
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