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Systems biology analysis of the proteomic alterations induced by MPP(+), a Parkinson's disease-related mitochondrial toxin

Parkinson's disease (PD) is a complex neurodegenerative disease whose etiology has not been completely characterized. Many cellular processes have been proposed to play a role in the neuronal damage and loss: defects in the proteosomal activity, altered protein processing, increased reactive ox...

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Detalles Bibliográficos
Autores principales: Monti, Chiara, Bondi, Heather, Urbani, Andrea, Fasano, Mauro, Alberio, Tiziana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313704/
https://www.ncbi.nlm.nih.gov/pubmed/25698928
http://dx.doi.org/10.3389/fncel.2015.00014