Dopamine induces the accumulation of insoluble prion protein and affects autophagic flux

Accumulation of protein aggregates is a histopathological hallmark of several neurodegenerative diseases, but in most cases the aggregation occurs without defined mutations or clinical histories, suggesting that certain endogenous metabolites can promote aggregation of specific proteins. One example...

Descripción completa

Detalles Bibliográficos
Autores principales: da Luz, Marcio H. M., Peres, Italo T., Santos, Tiago G., Martins, Vilma R., Icimoto, Marcelo Y., Lee, Kil S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313710/
https://www.ncbi.nlm.nih.gov/pubmed/25698927
http://dx.doi.org/10.3389/fncel.2015.00012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313710/
https://www.ncbi.nlm.nih.gov/pubmed/25698927
http://dx.doi.org/10.3389/fncel.2015.00012

Ejemplares similares