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Protein A Suppresses Immune Responses during Staphylococcus aureus Bloodstream Infection in Guinea Pigs

Staphylococcus aureus infection is not associated with the development of protective immunity, and disease relapses occur frequently. We hypothesize that protein A, a factor that binds immunoglobulin Fcγ and cross-links V(H)3 clan B cell receptors (IgM), is the staphylococcal determinant for host im...

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Detalles Bibliográficos
Autores principales: Kim, Hwan Keun, Falugi, Fabiana, Thomer, Lena, Missiakas, Dominique M., Schneewind, Olaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313907/
https://www.ncbi.nlm.nih.gov/pubmed/25564466
http://dx.doi.org/10.1128/mBio.02369-14