Membrane Anchoring of Epstein-Barr Virus gp42 Inhibits Fusion with B Cells Even with Increased Flexibility Allowed by Engineered Spacers

We recently described the architecture of the Epstein-Barr virus (EBV) fusion-triggering complex consisting of the EBV B cell receptor human leukocyte antigen (HLA) class II and the EBV-encoded proteins gp42 and gH/gL. The architecture of this structure positioned the main body of gp42, comprising t...

Descripción completa

Detalles Bibliográficos
Autores principales: Rowe, Cynthia L., Chen, Jia, Jardetzky, Theodore S., Longnecker, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313908/
https://www.ncbi.nlm.nih.gov/pubmed/25564465
http://dx.doi.org/10.1128/mBio.02285-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313908/
https://www.ncbi.nlm.nih.gov/pubmed/25564465
http://dx.doi.org/10.1128/mBio.02285-14

Ejemplares similares