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Inactivation of DAP12 in PMN Inhibits TREM1-Mediated Activation in Rheumatoid Arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by dysregulated and chronic systemic inflammatory responses that affect the synovium, bone, and cartilage causing damage to extra-articular tissue. Innate immunity is the first line of defense against invading pathogens and assists in...

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Detalles Bibliográficos
Autores principales: Chen, Xianghong, Eksioglu, Erika A., Carter, John D., Fortenbery, Nicole, Donatelli, Sarah S., Zhou, Junmin, Liu, Jinhong, Yang, Lili, Gilvary, Danielle, Djeu, Julie, Wei, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313943/
https://www.ncbi.nlm.nih.gov/pubmed/25642940
http://dx.doi.org/10.1371/journal.pone.0115116