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Inactivation of DAP12 in PMN Inhibits TREM1-Mediated Activation in Rheumatoid Arthritis
Rheumatoid arthritis (RA) is an autoimmune disease characterized by dysregulated and chronic systemic inflammatory responses that affect the synovium, bone, and cartilage causing damage to extra-articular tissue. Innate immunity is the first line of defense against invading pathogens and assists in...
Autores principales: | Chen, Xianghong, Eksioglu, Erika A., Carter, John D., Fortenbery, Nicole, Donatelli, Sarah S., Zhou, Junmin, Liu, Jinhong, Yang, Lili, Gilvary, Danielle, Djeu, Julie, Wei, Sheng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4313943/ https://www.ncbi.nlm.nih.gov/pubmed/25642940 http://dx.doi.org/10.1371/journal.pone.0115116 |
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