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Itch E3 Ubiquitin Ligase Positively Regulates TGF-β Signaling to EMT via Smad7 Ubiquitination

TGF-β regulates pleiotropic cellular responses including cell growth, differentiation, migration, apoptosis, extracellular matrix production, and many other biological processes. Although non-Smad signaling pathways are being increasingly reported to play many roles in TGF-β-mediated biological proc...

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Detalles Bibliográficos
Autores principales: Park, Su-hyun, Jung, Eun-Ho, Kim, Geun-Young, Kim, Byung-Chul, Lim, Jae Hyang, Woo, Chang-Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314125/
https://www.ncbi.nlm.nih.gov/pubmed/25518932
http://dx.doi.org/10.14348/molcells.2015.2120