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Liraglutide inhibits autophagy and apoptosis induced by high glucose through GLP-1R in renal tubular epithelial cells

Tubular atrophy and dysfunction is a critical process underlying diabetic nephropathy (DN). Understanding the mechanisms underlying renal tubular epithelial cell survival is important for the prevention of kidney failure associated with glucotoxicity. Autophagy is a cellular pathway involved in prot...

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Detalles Bibliográficos
Autores principales: ZHAO, X, LIU, G, SHEN, H, GAO, B, LI, X, FU, J, ZHOU, J, JI, Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314412/
https://www.ncbi.nlm.nih.gov/pubmed/25573030
http://dx.doi.org/10.3892/ijmm.2014.2052