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Glucose-regulated insulin production in the liver improves glycemic control in type 1 diabetic mice()
OBJECTIVE: Type 1 diabetes results from autoimmune destruction of beta-cells in the pancreas. Our objective is to reconstitute a glucose-responsive system in the liver to regulate hepatic insulin production for improving glycemic control in type 1 diabetes. METHODS: We have cloned the glucose-respon...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314533/ https://www.ncbi.nlm.nih.gov/pubmed/25685692 http://dx.doi.org/10.1016/j.molmet.2014.10.005 |