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SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function

OBJECTIVE: SIRT1 has been proposed to be a key signaling node linking changes in energy metabolism to transcriptional adaptations. Although SIRT1 overexpression is protective against diverse metabolic complications, especially in response to high-fat diets, studies aiming to understand the etiology...

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Detalles Bibliográficos
Autores principales: Boutant, Marie, Joffraud, Magali, Kulkarni, Sameer S., García-Casarrubios, Ester, García-Roves, Pablo M., Ratajczak, Joanna, Fernández-Marcos, Pablo J., Valverde, Angela M., Serrano, Manuel, Cantó, Carles
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314542/
https://www.ncbi.nlm.nih.gov/pubmed/25685699
http://dx.doi.org/10.1016/j.molmet.2014.12.008