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Cardiomyocyte glucagon receptor signaling modulates outcomes in mice with experimental myocardial infarction

OBJECTIVE: Glucagon is a hormone with metabolic actions that maintains normoglycemia during the fasting state. Strategies enabling either inhibition or activation of glucagon receptor (Gcgr) signaling are being explored for the treatment of diabetes or obesity. However, the cardiovascular consequenc...

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Detalles Bibliográficos
Autores principales: Ali, Safina, Ussher, John R., Baggio, Laurie L., Kabir, M. Golam, Charron, Maureen J., Ilkayeva, Olga, Newgard, Christopher B., Drucker, Daniel J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314543/
https://www.ncbi.nlm.nih.gov/pubmed/25685700
http://dx.doi.org/10.1016/j.molmet.2014.11.005