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Homo-β-amino acid containing MBP(85–99) analogs alleviate experimental autoimmune encephalomyelitis
MBP(85–99), an immuno-dominant epitope of myelin basic protein which binds to the major histocompatibility complex haplotype HLA-DR2 is widely implicated in the pathogenesis of multiple sclerosis. J5, an antagonist of MBP(85–99), that blocks the binding of MBP(85–99) to soluble HLA-DR2b much more ef...
Autores principales: | Kant, Ravi, Pasi, Shweta, Surolia, Avadhesha |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314633/ https://www.ncbi.nlm.nih.gov/pubmed/25644378 http://dx.doi.org/10.1038/srep08205 |
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