Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor

Retinoid X receptors (RXRs) act as homodimers or heterodimerisation partners of class II nuclear receptors. RXR homo- and heterodimers bind direct repeats of the half-site (A/G)G(G/T)TCA separated by 1 nucleotide (DR1). We present a structural characterization of RXR-DNA binding domain (DBD) homodim...

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Detalles Bibliográficos
Autores principales: Osz, Judit, McEwen, Alastair G., Poussin-Courmontagne, Pierre, Moutier, Emmanuel, Birck, Catherine, Davidson, Irwin, Moras, Dino, Rochel, Natacha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314640/
https://www.ncbi.nlm.nih.gov/pubmed/25645674
http://dx.doi.org/10.1038/srep08216

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314640/
https://www.ncbi.nlm.nih.gov/pubmed/25645674
http://dx.doi.org/10.1038/srep08216

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