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Identification of flubendazole as potential anti-neuroblastoma compound in a large cell line screen

Flubendazole was shown to exert anti-leukaemia and anti-myeloma activity through inhibition of microtubule function. Here, flubendazole was tested for its effects on the viability of in total 461 cancer cell lines. Neuroblastoma was identified as highly flubendazole-sensitive cancer entity in a scre...

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Detalles Bibliográficos
Autores principales: Michaelis, Martin, Agha, Bishr, Rothweiler, Florian, Löschmann, Nadine, Voges, Yvonne, Mittelbronn, Michel, Starzetz, Tatjana, Harter, Patrick N., Abhari, Behnaz A., Fulda, Simone, Westermann, Frank, Riecken, Kristoffer, Spek, Silvia, Langer, Klaus, Wiese, Michael, Dirks, Wilhelm G., Zehner, Richard, Cinatl, Jaroslav, Wass, Mark N., Cinatl, Jindrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314641/
https://www.ncbi.nlm.nih.gov/pubmed/25644037
http://dx.doi.org/10.1038/srep08202