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miR-19b regulates hTERT mRNA expression through targeting PITX1 mRNA in melanoma cells
Human telomerase reverse transcriptase (hTERT) plays a crucial role in cancer development. We previously identified paired-like homeodomain1 (PITX1) as an hTERT suppressor gene. However, the underlying mechanisms that are involved in the regulation of PITX1 remain unknown. Here, we report that the m...
Autores principales: | Ohira, Takahito, Naohiro, Sunamura, Nakayama, Yuji, Osaki, Mitsuhiko, Okada, Futoshi, Oshimura, Mitsuo, Kugoh, Hiroyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314654/ https://www.ncbi.nlm.nih.gov/pubmed/25643913 http://dx.doi.org/10.1038/srep08201 |
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