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The Phosphoinositide 3-Kinase Isoform PI3Kβ Regulates Osteoclast-Mediated Bone Resorption in Humans and Mice

OBJECTIVE: While phosphoinositide 3-kinases (PI3Ks) are involved in various intracellular signal transduction processes, the specific functions of the different PI3K isoforms are poorly understood. We have previously shown that the PI3Kβ isoform is required for arthritis development in the K/BxN ser...

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Detalles Bibliográficos
Autores principales: Győri, Dávid, Csete, Dániel, Benkő, Szilvia, Kulkarni, Suhasini, Mandl, Péter, Dobó-Nagy, Csaba, Vanhaesebroeck, Bart, Stephens, Len, Hawkins, Phillip T, Mócsai, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314683/
https://www.ncbi.nlm.nih.gov/pubmed/24719382
http://dx.doi.org/10.1002/art.38660