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Peripheral Calcitonin Gene-Related Peptide Receptor Activation and Mechanical Sensitization of the Joint in Rat Models of Osteoarthritis Pain

OBJECTIVE: To investigate the role of the sensory neuropeptide calcitonin gene-related peptide (CGRP) in peripheral sensitization in experimental models of osteoarthritis (OA) pain. METHODS: Experimental knee OA was induced in rats by intraarticular injection of monosodium iodoacetate (MIA) or by tr...

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Detalles Bibliográficos
Autores principales: Bullock, Craig M, Wookey, Peter, Bennett, Andrew, Mobasheri, Ali, Dickerson, Ian, Kelly, Sara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314689/
https://www.ncbi.nlm.nih.gov/pubmed/24719311
http://dx.doi.org/10.1002/art.38656