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NLRP1 inflammasome is activated in patients with medial temporal lobe epilepsy and contributes to neuronal pyroptosis in amygdala kindling-induced rat model

BACKGROUND: Temporal lobe epilepsy (TLE) is often characterized pathologically by severe neuronal loss in the hippocampus. Understanding the mechanisms of neuron death is key to preventing the neurodegeneration associated with TLE. However, the involvement of neuronal loss to the epileptogenic proce...

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Detalles Bibliográficos
Autores principales: Tan, Chen-Chen, Zhang, Jian-Guo, Tan, Meng-Shan, Chen, Hua, Meng, Da-Wei, Jiang, Teng, Meng, Xiang-Fei, Li, Ying, Sun, Zhen, Li, Meng-Meng, Yu, Jin-Tai, Tan, Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314732/
https://www.ncbi.nlm.nih.gov/pubmed/25626361
http://dx.doi.org/10.1186/s12974-014-0233-0