Aurora kinase B inhibition reduces the proliferation of metastatic melanoma cells and enhances the response to chemotherapy

BACKGROUND: The poor response to chemotherapy and the brief response to vemurafenib in metastatic melanoma patients, make the identification of new therapeutic approaches an urgent need. Interestingly the increased expression and activity of the Aurora kinase B during melanoma progression suggests i...

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Detalles Bibliográficos
Autores principales: Porcelli, Letizia, Guida, Gabriella, Quatrale, Anna E, Cocco, Tiziana, Sidella, Letizia, Maida, Immacolata, Iacobazzi, Rosa M, Ferretta, Anna, Stolfa, Diana A, Strippoli, Sabino, Guida, Stefania, Tommasi, Stefania, Guida, Michele, Azzariti, Amalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314759/
https://www.ncbi.nlm.nih.gov/pubmed/25623468
http://dx.doi.org/10.1186/s12967-015-0385-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314759/
https://www.ncbi.nlm.nih.gov/pubmed/25623468
http://dx.doi.org/10.1186/s12967-015-0385-4

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