Evidence that the presynaptic vesicle protein CSPalpha is a key player in synaptic degeneration and protection in Alzheimer’s disease

BACKGROUND: In Alzheimer’s disease synapse loss precedes neuronal loss and correlates best with impaired memory formation. However, the mechanisms underlying synaptic degeneration in Alzheimer’s disease are not well known. Further, it is unclear why synapses in AD cerebellum are protected from degen...

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Detalles Bibliográficos
Autores principales: Tiwari, Sachin S, d’Orange, Marie, Troakes, Claire, Shurovi, Badrun N, Engmann, Olivia, Noble, Wendy, Hortobágyi, Tibor, Giese, Karl P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314762/
https://www.ncbi.nlm.nih.gov/pubmed/25631211
http://dx.doi.org/10.1186/s13041-015-0096-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314762/
https://www.ncbi.nlm.nih.gov/pubmed/25631211
http://dx.doi.org/10.1186/s13041-015-0096-z

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