In vitro treatment of HepG2 cells with saturated fatty acids reproduces mitochondrial dysfunction found in nonalcoholic steatohepatitis

Activity of the oxidative phosphorylation system (OXPHOS) is decreased in humans and mice with nonalcoholic steatohepatitis. Nitro-oxidative stress seems to be involved in its pathogenesis. The aim of this study was to determine whether fatty acids are implicated in the pathogenesis of this mitochon...

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Detalles Bibliográficos
Autores principales: García-Ruiz, Inmaculada, Solís-Muñoz, Pablo, Fernández-Moreira, Daniel, Muñoz-Yagüe, Teresa, Solís-Herruzo, José A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314783/
https://www.ncbi.nlm.nih.gov/pubmed/25540128
http://dx.doi.org/10.1242/dmm.018234

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314783/
https://www.ncbi.nlm.nih.gov/pubmed/25540128
http://dx.doi.org/10.1242/dmm.018234

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