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A global microRNA screen identifies regulators of the ErbB receptor signaling network

BACKGROUND: The growth factor heregulin (HRG) potently stimulates epithelial cell survival and proliferation through the binding of its cognate receptor ErbB3 (also known as HER3). ErbB3-dependent signal transmission relies on the dimerization partner ErbB2, a receptor tyrosine kinase that is freque...

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Detalles Bibliográficos
Autores principales: Bischoff, Annabell, Bayerlová, Michaela, Strotbek, Michaela, Schmid, Simone, Beissbarth, Tim, Olayioye, Monilola A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4314810/
https://www.ncbi.nlm.nih.gov/pubmed/25630670
http://dx.doi.org/10.1186/s12964-015-0084-z