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Chlorotoxin-conjugated onconase as a potential anti-glioma drug

Gliomas are rarely curable malignant brain tumors arising from normal glial cells. The scorpion-derived small peptide, chlorotoxin (CTX), can selectively bind malignant gliomas. In the present study, a CTX-conjugated onconase (Onc), a small cytotoxic ribonuclease, was prepared as a potential anti-gl...

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Detalles Bibliográficos
Autores principales: WANG, XIAOMIN, GUO, ZHANYUN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315000/
https://www.ncbi.nlm.nih.gov/pubmed/25663909
http://dx.doi.org/10.3892/ol.2014.2835