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Cross-drug resistance to sunitinib induced by doxorubicin in endothelial cells

Multiple drug resistance remains an unsolved problem in cancer therapy. A previous study has demonstrated that the chemotherapeutic drug doxorubicin (Dox) induced upregulation of P-glycoprotein in endothelial cells, resulting in a 20-fold increase in drug resistance and reduced efficiency of doxorub...

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Detalles Bibliográficos
Autores principales: HUANG, LIMIN, HU, CHAOQUAN, DI BENEDETTO, MÉLANIE, VARIN, RÉMI, LIU, JIELIN, JIN, JIAN, WANG, LI, VANNIER, JEAN-PIERRE, JANIN, ANNE, LU, HE, LI, HONG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315062/
https://www.ncbi.nlm.nih.gov/pubmed/25663899
http://dx.doi.org/10.3892/ol.2014.2819