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Trisomy 8 Acute Myeloid Leukemia Analysis Reveals New Insights of DNA Methylome with Identification of HHEX as Potential Diagnostic Marker

Trisomy 8 acute myeloid leukemia (AML) is the commonest numerical aberration in AML. Here we present a global analysis of trisomy 8 AML using methylated DNA immunoprecipitation-sequencing (MeDIP-seq). The study is based on three diagnostic trisomy 8 AML and their parallel relapse status in addition...

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Detalles Bibliográficos
Autores principales: Saied, Marwa H, Marzec, Jacek, Khalid, Sabah, Smith, Paul, Molloy, Gael, Young, Bryan D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315123/
https://www.ncbi.nlm.nih.gov/pubmed/25674022
http://dx.doi.org/10.4137/BIC.S19614