Exome Sequencing of Normal and Isogenic Transformed Human Colonic Epithelial Cells (HCECs) Reveals Novel Genes Potentially Involved in the Early Stages of Colorectal Tumorigenesis

BACKGROUND: We have generated a series of isogenically derived immortalized human colonic epithelial cell (HCEC 1CT and HCEC 2CT) lines, including parental un-immortalized normal cell strains. The CDK4 and hTERT immortalized colonic epithelial cell line (HCEC 1CT) is initially karyotypically normal...

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Detalles Bibliográficos
Autores principales: Zhang, Lu, Kim, Sang Bum, Jia, Gaoxiang, Buhemeida, Abdelbaset, Dallol, Ashraf, Wright, Woodring E, Fornace, Albert J, Al-Qahtani, Mohammed, Shay, Jerry W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315167/
https://www.ncbi.nlm.nih.gov/pubmed/25923178
http://dx.doi.org/10.1186/1471-2164-16-S1-S8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315167/
https://www.ncbi.nlm.nih.gov/pubmed/25923178
http://dx.doi.org/10.1186/1471-2164-16-S1-S8

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