Cargando…

Protein kinase Gin4 negatively regulates flippase function and controls plasma membrane asymmetry

Plasma membrane function requires distinct leaflet lipid compositions. Two of the P-type ATPases (flippases) in yeast, Dnf1 and Dnf2, translocate aminoglycerophospholipids from the outer to the inner leaflet, stimulated via phosphorylation by cortically localized protein kinase Fpk1. By monitoring F...

Descripción completa

Detalles Bibliográficos
Autores principales: Roelants, Françoise M., Su, Brooke M., von Wulffen, Joachim, Ramachandran, Subramaniam, Sartorel, Elodie, Trott, Amy E., Thorner, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315245/
https://www.ncbi.nlm.nih.gov/pubmed/25646086
http://dx.doi.org/10.1083/jcb.201410076