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Protein kinase Gin4 negatively regulates flippase function and controls plasma membrane asymmetry

Plasma membrane function requires distinct leaflet lipid compositions. Two of the P-type ATPases (flippases) in yeast, Dnf1 and Dnf2, translocate aminoglycerophospholipids from the outer to the inner leaflet, stimulated via phosphorylation by cortically localized protein kinase Fpk1. By monitoring F...

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Detalles Bibliográficos
Autores principales:	Roelants, Françoise M., Su, Brooke M., von Wulffen, Joachim, Ramachandran, Subramaniam, Sartorel, Elodie, Trott, Amy E., Thorner, Jeremy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315245/ https://www.ncbi.nlm.nih.gov/pubmed/25646086 http://dx.doi.org/10.1083/jcb.201410076

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