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Perlecan is recruited by dystroglycan to nodes of Ranvier and binds the clustering molecule gliomedin

Fast neural conduction requires accumulation of Na(+) channels at nodes of Ranvier. Dedicated adhesion molecules on myelinating cells and axons govern node organization. Among those, specific laminins and dystroglycan complexes contribute to Na(+) channel clustering at peripheral nodes by unknown me...

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Detalles Bibliográficos
Autores principales: Colombelli, Cristina, Palmisano, Marilena, Eshed-Eisenbach, Yael, Zambroni, Desirée, Pavoni, Ernesto, Ferri, Cinzia, Saccucci, Stefania, Nicole, Sophie, Soininen, Raija, McKee, Karen K., Yurchenco, Peter D., Peles, Elior, Wrabetz, Lawrence, Feltri, M. Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315246/
https://www.ncbi.nlm.nih.gov/pubmed/25646087
http://dx.doi.org/10.1083/jcb.201403111