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Perlecan is recruited by dystroglycan to nodes of Ranvier and binds the clustering molecule gliomedin
Fast neural conduction requires accumulation of Na(+) channels at nodes of Ranvier. Dedicated adhesion molecules on myelinating cells and axons govern node organization. Among those, specific laminins and dystroglycan complexes contribute to Na(+) channel clustering at peripheral nodes by unknown me...
Autores principales: | Colombelli, Cristina, Palmisano, Marilena, Eshed-Eisenbach, Yael, Zambroni, Desirée, Pavoni, Ernesto, Ferri, Cinzia, Saccucci, Stefania, Nicole, Sophie, Soininen, Raija, McKee, Karen K., Yurchenco, Peter D., Peles, Elior, Wrabetz, Lawrence, Feltri, M. Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315246/ https://www.ncbi.nlm.nih.gov/pubmed/25646087 http://dx.doi.org/10.1083/jcb.201403111 |
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