Cargando…

Unipotent, Atoh1(+) progenitors maintain the Merkel cell population in embryonic and adult mice

Resident progenitor cells in mammalian skin generate new cells as a part of tissue homeostasis. We sought to identify the progenitors of Merkel cells, a unique skin cell type that plays critical roles in mechanosensation. We found that some Atoh1-expressing cells in the hairy skin and whisker follic...

Descripción completa

Detalles Bibliográficos
Autores principales: Wright, Margaret C., Reed-Geaghan, Erin G., Bolock, Alexa M., Fujiyama, Tomoyuki, Hoshino, Mikio, Maricich, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315254/
https://www.ncbi.nlm.nih.gov/pubmed/25624394
http://dx.doi.org/10.1083/jcb.201407101