Decoupling of evolutionary changes in transcription factor binding and gene expression in mammals

To understand the evolutionary dynamics between transcription factor (TF) binding and gene expression in mammals, we compared transcriptional output and the binding intensities for three tissue-specific TFs in livers from four closely related mouse species. For each transcription factor, TF-dependen...

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Detalles Bibliográficos
Autores principales: Wong, Emily S., Thybert, David, Schmitt, Bianca M., Stefflova, Klara, Odom, Duncan T., Flicek, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315291/
https://www.ncbi.nlm.nih.gov/pubmed/25394363
http://dx.doi.org/10.1101/gr.177840.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315291/
https://www.ncbi.nlm.nih.gov/pubmed/25394363
http://dx.doi.org/10.1101/gr.177840.114

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