Violation of the 12/23 rule of genomic V(D)J recombination is common in lymphocytes

V(D)J genomic recombination joins single gene segments to encode an extensive repertoire of antigen receptor specificities in T and B lymphocytes. This process initiates with double-stranded breaks adjacent to conserved recombination signal sequences that contain either 12- or 23-nucleotide spacer r...

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Detalles Bibliográficos
Autores principales: Parkinson, Nicholas J., Roddis, Matthew, Ferneyhough, Ben, Zhang, Gang, Marsden, Adam J., Maslau, Siarhei, Sanchez-Pearson, Yasmin, Barthlott, Thomas, Humphreys, Ian R., Ladell, Kristin, Price, David A., Ponting, Chris P., Hollander, Georg, Fischer, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315296/
https://www.ncbi.nlm.nih.gov/pubmed/25367293
http://dx.doi.org/10.1101/gr.179770.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315296/
https://www.ncbi.nlm.nih.gov/pubmed/25367293
http://dx.doi.org/10.1101/gr.179770.114

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