Cupid: simultaneous reconstruction of microRNA-target and ceRNA networks

We introduce a method for simultaneous prediction of microRNA–target interactions and their mediated competitive endogenous RNA (ceRNA) interactions. Using high-throughput validation assays in breast cancer cell lines, we show that our integrative approach significantly improves on microRNA–target p...

Descripción completa

Detalles Bibliográficos
Autores principales: Chiu, Hua-Sheng, Llobet-Navas, David, Yang, Xuerui, Chung, Wei-Jen, Ambesi-Impiombato, Alberto, Iyer, Archana, Kim, Hyunjae Ryan, Seviour, Elena G., Luo, Zijun, Sehgal, Vasudha, Moss, Tyler, Lu, Yiling, Ram, Prahlad, Silva, José, Mills, Gordon B., Califano, Andrea, Sumazin, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315299/
https://www.ncbi.nlm.nih.gov/pubmed/25378249
http://dx.doi.org/10.1101/gr.178194.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315299/
https://www.ncbi.nlm.nih.gov/pubmed/25378249
http://dx.doi.org/10.1101/gr.178194.114

Ejemplares similares