Evolutionary Diagnosis of non-synonymous variants involved in differential drug response

BACKGROUND: Many pharmaceutical drugs are known to be ineffective or have negative side effects in a substantial proportion of patients. Genomic advances are revealing that some non-synonymous single nucleotide variants (nsSNVs) may cause differences in drug efficacy and side effects. Therefore, it...

Descripción completa

Detalles Bibliográficos
Autores principales: Gerek, Nevin Z, Liu, Li, Gerold, Kristyn, Biparva, Pegah, Thomas, Eric D, Kumar, Sudhir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315320/
https://www.ncbi.nlm.nih.gov/pubmed/25952014
http://dx.doi.org/10.1186/1755-8794-8-S1-S6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315320/
https://www.ncbi.nlm.nih.gov/pubmed/25952014
http://dx.doi.org/10.1186/1755-8794-8-S1-S6

Ejemplares similares