An Efficient Strategy for Heterologous Expression and Purification of Active Peptide Hainantoxin-IV

Hainantoxin-IV (HNTX-IV) from the venom of the spider Selenocosmia hainana is a potent antagonist that specifically inhibits the tetrodotoxin-sensitive (TTX-S) sodium channels. The toxin peptide consists of 35 amino acids and adopts a typical inhibitory cystine knot (ICK) motif. To obtain adequate H...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Huang, Peng-Fei, Meng, Er, Li, Wen-Ying, Zhou, Lu, Zhu, Ling-Yun, Wu, Lei, Li, Meng-Jie, Liang, Song-Ping, Zhang, Dong-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315428/
https://www.ncbi.nlm.nih.gov/pubmed/25647561
http://dx.doi.org/10.1371/journal.pone.0117099

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315428/
https://www.ncbi.nlm.nih.gov/pubmed/25647561
http://dx.doi.org/10.1371/journal.pone.0117099

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