Compartmentalization of GABA Synthesis by GAD67 Differs between Pancreatic Beta Cells and Neurons

The inhibitory neurotransmitter GABA is synthesized by the enzyme glutamic acid decarboxylase (GAD) in neurons and in pancreatic β-cells in islets of Langerhans where it functions as a paracrine and autocrine signaling molecule regulating the function of islet endocrine cells. The localization of th...

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Detalles Bibliográficos
Autores principales: Kanaani, Jamil, Cianciaruso, Chiara, Phelps, Edward A., Pasquier, Miriella, Brioudes, Estelle, Billestrup, Nils, Baekkeskov, Steinunn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315522/
https://www.ncbi.nlm.nih.gov/pubmed/25647668
http://dx.doi.org/10.1371/journal.pone.0117130

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315522/
https://www.ncbi.nlm.nih.gov/pubmed/25647668
http://dx.doi.org/10.1371/journal.pone.0117130

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