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Development of the designed ankyrin repeat protein (DARPin) G3 for HER2 molecular imaging

PURPOSE: Human epidermal growth factor receptor-2 (HER2) overexpression is a predictor of response to anti-HER2 therapy in breast and gastric cancer. Currently, HER2 status is assessed by tumour biopsy, but this may not be representative of the larger tumour mass or other metastatic sites, risking m...

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Detalles Bibliográficos
Autores principales: Goldstein, Robert, Sosabowski, Jane, Livanos, Maria, Leyton, Julius, Vigor, Kim, Bhavsar, Gaurav, Nagy-Davidescu, Gabriela, Rashid, Mohammed, Miranda, Enrique, Yeung, Jenny, Tolner, Berend, Plückthun, Andreas, Mather, Stephen, Meyer, Tim, Chester, Kerry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315530/
https://www.ncbi.nlm.nih.gov/pubmed/25391547
http://dx.doi.org/10.1007/s00259-014-2940-2