Optimization of caseinate-coated simvastatin-zein nanoparticles: improved bioavailability and modified release characteristics

The current study focuses on utilization of the natural biocompatible polymer zein to formulate simvastatin (SMV) nanoparticles coated with caseinate, to improve solubility and hence bioavailability, and in addition, to modify SMV-release characteristics. This formulation can be utilized for oral or...

Descripción completa

Detalles Bibliográficos
Autores principales: Ahmed, Osama AA, Hosny, Khaled M, Al-Sawahli, Majid M, Fahmy, Usama A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315536/
https://www.ncbi.nlm.nih.gov/pubmed/25670883
http://dx.doi.org/10.2147/DDDT.S76194

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315536/
https://www.ncbi.nlm.nih.gov/pubmed/25670883
http://dx.doi.org/10.2147/DDDT.S76194

Ejemplares similares