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Fractionation of electrograms is caused by colocalized conduction block and connexin disorganization in the absence of fibrosis as AF becomes persistent in the goat model

BACKGROUND: Electrogram fractionation and atrial fibrosis are both thought to be pathophysiological hallmarks of evolving persistence of atrial fibrillation (AF), but recent studies in humans have shown that they do not colocalize. The interrelationship and relative roles of fractionation and fibrot...

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Detalles Bibliográficos
Autores principales: Kirubakaran, Senthil, Chowdhury, Rasheda A., Hall, Mark C.S., Patel, Pravina M., Garratt, Clifford J., Peters, Nicholas S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315883/
https://www.ncbi.nlm.nih.gov/pubmed/25444850
http://dx.doi.org/10.1016/j.hrthm.2014.10.027