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Mechanisms of cell death pathway activation following drug-induced inhibition of mitochondrial complex I
Respiratory complex I inhibition by drugs and other chemicals has been implicated as a frequent mode of mitochondria-mediated cell injury. However, the exact mechanisms leading to the activation of cell death pathways are incompletely understood. This study was designed to explore the relative contr...
Autores principales: | Imaizumi, Naoki, Kwang Lee, Kang, Zhang, Carmen, Boelsterli, Urs A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315936/ https://www.ncbi.nlm.nih.gov/pubmed/25625582 http://dx.doi.org/10.1016/j.redox.2015.01.005 |
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