Targeting histone lysine demethylases — Progress, challenges, and the future()

N-Methylation of lysine and arginine residues has emerged as a major mechanism of transcriptional regulation in eukaryotes. In humans, N(ε)-methyllysine residue demethylation is catalysed by two distinct subfamilies of demethylases (KDMs), the flavin-dependent KDM1 subfamily and the 2-oxoglutarate-...

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Detalles Bibliográficos
Autores principales: Thinnes, Cyrille C., England, Katherine S., Kawamura, Akane, Chowdhury, Rasheduzzaman, Schofield, Christopher J., Hopkinson, Richard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316176/
https://www.ncbi.nlm.nih.gov/pubmed/24859458
http://dx.doi.org/10.1016/j.bbagrm.2014.05.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4316176/
https://www.ncbi.nlm.nih.gov/pubmed/24859458
http://dx.doi.org/10.1016/j.bbagrm.2014.05.009

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